The NRA will be asked to conduct a safety audit of the M20 stretch of motorway in Limerick between junctions 4 and 5 after Saturday’s fatla crash which claimed the life of a three year old girlTHE National Roads Authority are to be asked to conduct a review and safety audit of the stretch of M20 motorway between junctions 4 and 5 following the death of three year old girl on Saturday night in a two-car collision.Kellycia Nudiri was pronounced dead at the University Hospital Limerick on Saturday night after the car she was travelling in collided with another vehicle on the M20 motorway near the Patrickswell exit.It is understood that the car in which Kellycia was in, along with her parents and twin brother, swerved to avoid a car that had taken its own evasive action.Sign up for the weekly Limerick Post newsletter Sign Up Subsequently, the Nudiri car driven by Kellycia’s mother, rolled several times before come to a rest on its roof.The three-year-old girl had been ejected from her seat and was trapped in her car.She suffered serious head injuries and died later in hospital.Other passengers were treated for minor injuries.Originally from Democratic Republic of Congo the Nudiri family moved to Abbeyfeale recently and have been left in mourning following the tragic events.As the local community rallies to offer assistance, Fianna Fail TD, Deputy Niall Collins who lives in the Patrickswell area has said that he will call on the National Roads Authority (NRA) this week to carry out a safety audit of the stretch of road.“Firstly, I’d like to express my sympathy and condolences to the family bereaved after Saturday’s accident.“The local communities in Patrickswell and Abbeyfeale are very shocked and upset following the accident.“Over the years there have been a number of serious accidents on this stretch of motorway.“This week I will ask the NRA to conduct a review and safety audit to assess whether any measures are needed to enhance road safety at this location.”Gardai are investigating and a forensic collision experts have carried out initial analysis of the incident.However, witnesses to the crash are asked to contact Roxboro Road Garda Station on 061-214340 or the Garda Confidential Line 1800 666 111. NewsNRA to audit M20 after fatal Limerick toddler crashBy Staff Reporter – September 19, 2016 1224 Predictions on the future of learning discussed at Limerick Lifelong Learning Festival Facebook Print Limerick’s National Camogie League double header to be streamed live Email WhatsApp WATCH: “Everyone is fighting so hard to get on” – Pat Ryan on competitive camogie squads Limerick Ladies National Football League opener to be streamed live Previous articleCompetition winnerNext article#WATCH Limerick 2030 plan to see €500m redevelopment Staff Reporterhttp://www.limerickpost.ie RELATED ARTICLESMORE FROM AUTHOR Limerick Artist ‘Willzee’ releases new Music Video – “A Dream of Peace” TAGSfeaturedGardaílimerickniall collinsNRA Twitter Advertisement Linkedin Billy Lee names strong Limerick side to take on Wicklow in crucial Division 3 clash
Read Full Story A newly discovered cellular messaging mechanism could lead to a new way to deliver therapeutics to tissues affected by disease, according to a new study from Harvard T.H. Chan School of Public Health. Researchers found that a type of extracellular vesicle (EV) — a sac secreted by cells that contains proteins and RNA molecules — known as ARMMs also carries receptors that allow signaling without direct contact between cells. This capability may make ARMMs uniquely suited to be engineered to send therapeutics directly to affected areas of the body.“EVs are like messages in a bottle between cells,” said senior author Quan Lu, associate professor of environmental genetics and pathophysiology. “We think that within the next few years, we may be able to swap the endogenous molecules in ARMMs for therapeutic cargos — such as antibodies — and to engineer ARMMs to home in on a particular tissue.”The study was published online Sept. 27, 2017 in Nature Communications.There are an estimated 37 trillion cells in the human body — and 100 times that many EVs. They circulate in the blood and other bodily fluids and are involved in processes such as coagulation and the immune response. They can also be hijacked to spread cancer or viruses like HIV and Ebola.EVs are generating a great deal of interest in the biotechnology field. Researchers believe that the molecules they carry include the fingerprints of disease and harmful environmental exposures. Work is already underway on developing a “liquid biopsy” to test EVs in a drop of blood.Previous work by Lu’s lab described the body’s mechanism for producing ARMMs. Unlike other EVs, which are generated within cells, ARMMs are secreted directly from the plasma membrane at the cell’s surface. Although the physiological function of ARMMs remains unknown, the way that they are made may make them uniquely suited to carry certain molecules.In the current study, the researchers found that ARMMs contain molecules used for NOTCH signaling, a type of intercellular communication that normally requires cell-to-cell contact. NOTCH receptors are plasma membrane proteins involved in critical physiological roles such as embryonic development, tissue homeostasis, and stem cell function. According to the new findings, ARMMs are able to facilitate NOTCH receptor signaling at a distance.“Our research on ARMMs has tremendous potential for therapeutics and public health,” Lu said. While other researchers have explored using EVs to deliver therapeutics, directing them within the body has been an obstacle. Lu believes that ARMMs provide a way past that barrier, and he was recently awarded a patent for generating, isolating, and engineering ARMMs. “It will likely be at least 10 years before we see these methods used in a clinical setting,” Lu said. “But the path forward is clear.” The study’s first author was Qiyu Wang, a research associate at Harvard Chan School.This study was supported in part by a National Institutes of Health R01grant (R01 HL114769) and by funding from the Blavatnik Biomedical Accelerator Fund.
El Gobernador Wolf anuncia un programa de subvenciones de $225 millones para pequeñas empresas afectadas por la COVID-19
SHARE Email Facebook Twitter Economy, Español, Press Release El Gobernador Tom Wolf hoy anunció un programa de subvenciones de alcance estatal de $225 millones para apoyar a las pequeñas empresas que se vieron afectadas por la crisis de salud pública producida por la COVID-19 y la posterior orden de cierre de empresas.“A medida que atravesamos la pandemia de COVID-19 y nos centramos en la reapertura de nuestro estado, debemos ayudar a todos los residentes de Pennsylvania a recuperarse. Necesitamos brindar asistencia a aquellos que se vieron perjudicados por la pandemia y la recesión económica resultante”, dijo el Gobernador Wolf. “Este nuevo programa brindará apoyo directo a las empresas perjudicadas para cubrir los gastos operativos durante el cierre y la transición a la reapertura”.La financiación se desarrolló en colaboración con los legisladores estatales y se asignó a través del presupuesto estatal recientemente promulgado, que incluyó $2.6 mil millones en fondos de estímulo federal a través de la Ley federal de Ayuda, Alivio y Seguridad Económica por el Coronavirus (Ley CARES), de los cuales $225 millones se destinaron como medidas de alivio para pequeñas empresas.El Departamento de Desarrollo Comunitario y Económico (DCED, por sus siglas en inglés) distribuirá los fondos a las Instituciones Financieras de Desarrollo Comunitario (CDFI, por sus siglas en inglés), que luego administrarán los fondos en forma de subvenciones.Las empresas elegibles podrán usar las subvenciones para cubrir los gastos operativos durante el cierre y la transición a la reapertura, y para recibir asistencia técnica, que incluye la capacitación y la orientación de los propietarios de empresas a medida que se estabilizan y reabren sus negocios.Los fondos estarán disponibles mediante tres programas:$100 millones para el Programa de revitalización de empresas de la calle principal (Main Street Business Revitalization Program) para pequeñas empresas que sufrieron pérdidas producto de la orden del gobernador del 19 de marzo de 2020 relacionada con el cierre de todas las empresas que no son de soporte vital y que tienen o tendrán gastos para adaptarse a nuevas operaciones comerciales relacionadas con la COVID-19;$100 millones para el Programa de revitalización de empresas históricamente desfavorecidas (Historically Disadvantaged Business Revitalization Program) para pequeñas empresas que sufrieron pérdidas producto de la orden de cierre de empresas, que tienen o tendrán gastos para adaptarse a las nuevas operaciones comerciales relacionadas con la COVID-19, y en las que las personas con desventajas sociales y económicas poseen al menos un 51% de interés y también controlan la gestión y las operaciones comerciales diarias.$25 millones para el Programa de aplazamiento de pago de préstamos y reserva de pérdidas (Loan Payment Deferment and Loss Reserve Program), que dará a las Instituciones Financieras de Desarrollo Comunitario (CDFI) la oportunidad de ofrecer tolerancia y alivio respecto de los pagos a las empresas de cartera existentes que están luchando debido a las repercusiones de la COVID, así como fortalecer la posición financiera de las CDFI que están sufriendo un aumento significativo de los incumplimientos en sus carteras de préstamos existentes.“Quiero agradecer al Gobernador Wolf por comprometer su liderazgo en la Asamblea General para informar el proceso de trasladar la ayuda federal a los más perjudicados por la pandemia de COVID-19. También quiero agradecer al liderazgo del bloque demócrata del Senado que colaboró con nuestros miembros para formular un plan estratégico para el despliegue de casi $4 mil millones en asistencia federal”, dijo el Senador estatal John Blake (demócrata por Lackawanna). “El Programa de revitalización de empresas de la calle principal es un reflejo de esa cooperación y liderazgo y se reunirá con los propietarios de pequeñas empresas de Pennsylvania allí donde se encuentran, en la calle principal, luego de casi tres meses de ventas a pérdida o sin ventas. Permitirá que los propietarios de pequeñas empresas en todo el Estado cumplan con los pagos de sus seguros, alquileres, primas de seguros médicos, impuestos locales y otros gastos que de otro modo no podrían cubrir debido a la pérdida de ventas. Finalmente, quiero agradecer a las 17 CDFI de todo el estado, igual que al DCED, por su profesionalismo, agilidad, urgencia y dedicación para llevar esta financiación federal a las pequeñas empresas que más lo necesitan lo más rápido posible”.“Los Programas de revitalización de empresas de la calle principal y de empresas históricamente desfavorecidas brindarán medidas de alivio bienvenidas a las empresas familiares en los vecindarios de todo el estado. Desde que comenzó esta pandemia, hemos escuchado las necesidades de los talleres de carrocería de automóviles, las peluquerías, las esteticistas, los dueños de pizzerías, los establecimientos de soul food y otras empresas en nuestras comunidades. Las necesidades de estas empresas que no pudieron obtener la ayuda que tanto necesitaban de otros programas estatales y federales fueron una prioridad en el anuncio del Programa PA CARES el 29 de abril en nuestro bloque Demócrata del Senado, dijo el senador estatal Vincent Hughes (D-Philadelphia/Montgomery). “Durante meses, mi oficina ha trabajado con una red de organizaciones comunitarias confiables que tienen una trayectoria comprobada de trabajo con nuestras pequeñas empresas, las CDFI, para encontrar una solución para prestar asistencia a las empresas de nuestro vecindario. Creo que estos programas son esa solución. Todavía hay más trabajo por hacer, pero estos programas son una victoria para Pennsylvania y sus pequeñas empresas”.“Las pequeñas empresas se llevaron la peor parte de las repercusiones económicas de la pandemia. Esta inversión es un buen primer paso hacia su recuperación y la recuperación de las comunidades en todo el estado”, dijo el líder demócrata de la Cámara de Representantes, Frank Dermody. “Este programa beneficiará a múltiples industrias diversas, propuesto por muchos miembros en la legislatura, incluidos los diputados Jared Solomon, Morgan Cephas, Jake Wheatley, Ryan Bizzarro, Chris Sappey y Melissa Shusterman”.La PA CDFI Network es un grupo de 17 instituciones financieras de desarrollo comunitario con sede en Pennsylvania que principalmente brindan opciones de financiamiento a pequeñas empresas.“Nos complace trabajar con el Gobernador en el Programa de asistencia estatal a las pequeñas empresas a causa de la COVID-19 (COVID-19 Relief Statewide Small Business Assistance) para brindar oportunidades económicas a los afectados por la pandemia de COVID-19”, dijo James Burnett, vicepresidente de la PA CDFI Network. “Sabemos lo importante que es respaldar a las empresas más pequeñas y vulnerables en todo el estado, incluidas las empresas históricamente desfavorecidas y de la calle principal”.Hay más información disponible en el sitio web de DCED.View this information in English. June 08, 2020 El Gobernador Wolf anuncia un programa de subvenciones de $225 millones para pequeñas empresas afectadas por la COVID-19
This house at 50 Dauphin Tce, Highgate Hill, was one of the most viewed property listings of 2019.THEY are owned by some of the state’s most high profile players and range from the outlandish and opulent to charming heroes of Queensland’s heritage.Some spectacular properties hit the market in 2019, but when it comes to home hunting, potential buyers have varying tastes, according to the most popular listings of 2019 on Realestate.com.au.In Queensland, the 10 most viewed properties of the year include a riverfront mansion owned by Terry Peabody, a James Bond inspired modern masterpiece, and a house with a bowling alley in the humble suburb of Stafford.These were the 10 hottest residential property listings in Queensland in 2019:THE 10 MOST VIEWED HOME LISTINGS OF 2019 IN QUEENSLAND 1. 70 Leichhardt Crescent, Barellan Point This property at 70 Leichhardt Crescent, Barellan Point, was the most viewed listing in Queensland in 2019.From the air, it looks like little more than a shed, but it’s the lifestyle this acreage retreat offers that really adds to its appeal.And possibly the fact it was owned by Brisbane radio personality Robin Bailey.Tucked away on the outskirts of Brisbane in a suburb of Ipswich, the incredibly private property at 70 Leichhardt Crescent comprises a huge 5777 sqm of land overlooking the Brisbane River. This property at 70 Leichhardt Cres, Barellan Point, is under contract.The three bedroom home has gone under contract after eight weeks on the market, with a middle-aged couple from Springfield the lucky buyers.The property had been advertised with a $495,000 price tag, but the sale price has not been disclosed as the deal is not yet unconditional. Marketing agent Neil Mundy of Ray White – Ipswich said the buyers signed the contract the same day Ms Bailey flew to India.Ms Bailey described the trip on social media as a way to reconnect with her sons following the death of her husband, Sean Pickwell, to cancer in September. Robin Bailey and her husband, Sean, who died from liver cancer this year. Picture: Annette Dew.Despite being on the river, Mr Mundy said the property was unaffected by the floods in 1974, 2011 and 2013.He said there were four offers, but the lucky buyer fell in love with the land, the layout and the views.“The biggest thing for me as an agent is the quietness — there’s no noise,” Mr Mundy said.“You can walk outside in your dressing gown and no one would know.”2. 15 Towers Street, Ascot This house at 15 Towers Street, Ascot, was the second most viewed listing of 2019 in Queensland.No expense was spared to create this statement property, which made headlines when it hit the market earlier this year with an $8.8 million price tag and the promise of a free luxury car and free wine.The Lamborghini has since sold, but the house and the wine are still up for grabs — although no longer with a price guide.“I had four people want to buy the car, not the house — it was pretty weird,” Zephyr Industries director Brayden Larkin said.The four-storey home at, 15 Towers St, Ascot, was built by Zephyr Industries and has five bedrooms, seven bathrooms and a seven-car garage. This house at 15 Towers Street, Ascot, is for sale.Mr Larkin said the original 1920s Queenslander home had just won Best Renovation in Australia in its category at the Master Builders Awards. “It’s pretty different,” he said.“It’s big, got two pools, comes with a lot of wine and has every feature under the sun.”Mr Larkin said the property had attracted interest from everyone from young professionals to local families and overseas buyers.The house, named Belvedere, features a temperature-controlled wine cellar (3000 bottles) with wine tasting room, and includes two barrels of custom wine made specifically for the home by Gerler Wines.An elevator, cinema, two pools, and a roof-top terrace with private six-seater spa are part of the home’s luxe mix. This property at 15 Towers Street, Ascot, certainly makes a statement.The property is for sale through Matt Lancashire and Patrick Goldsworthy of Ray White – New Farm.3. 50 Dauphin Terrace, Highgate Hill The view from the verandah at 50 Dauphin Tce, Highgate Hill.This property, just 2.5km from Brisbane’s CBD, attracted lots of attention when it hit the market with $11 million hopes.The trophy home at 50 Dauphin Terrace has a two-street frontage, two self-contained guest quarters, 60m of river frontage, a pontoon for a 60m vessel, seven bedrooms, four bathrooms, parking for five cars, a 23m gas-heated pool, four decks, an electronic boat lift and a boathouse.The huge house sits on almost 4000 sqm of prime real estate — a site where General Douglas MacArthur once led the Pacific campaign. This house at 50 Dauphin Tce, Highgate Hill, was the third most viewed listing in Queensland this year.4. 55 Courageous Court, Newport This home at 55 Courageous Court, Newport, was one of the most viewed listings of 2019.A mind-blowing home that can be turned into a 200-seat concert theatre was one of the hottest houses in Queensland — and the country — this year.The house sits on a massive 3,557 sqm block in Brisbane’s north and is being built on such a grand scale that the deck has got to be one of the largest ever seen in a home in the city.That’s because the owner of 55 Courageous Court, Newport secured permission to not just build a wraparound deck spanning 180 degrees of the canal site, but also the largest pontoon on the peninsula, which can accommodate a 120 foot super yacht.The property also has a caretaker’s quarters, plus a master suite that can be turned into a self-contained “granny flat”, as well as the grandeur of three storey high ceilings, floor-to-ceiling glass windows, a lift, electric blinds, ducted airconditioning systems, LED lights and smart controls with central CBUS hubs.Each bedroom comes with its own walk-in robe and balcony access plus a bathroom big enough to accommodate an oversized spa along with a shower and separate toilet.There is also a large shed with office space, a private ramp for small boats, and capacity to store 100,000 gallons of water.The property is still for sale via expressions of interest. This house at 55 Courageous Court, Newport, is for sale.5. 24 Cayman Crescent, Raby Bay This house at 24 Cayman Crescent, Raby Bay, was one of the hottest listings of 2019.This Mediterranean inspired home in Raby Bay has been on the market since mid 2018, but was still one of the most popular homes searched on realestate.com.au in 2019.The six-bedroom, four-bathroom house at 24 Cayman Cres is on a 1247sq m corner block and has a 30m water frontage overlooking the bay.The property was initially listed for $6.6 million, but has been reduced to offers over $4.9 million, which piqued interest among would-be buyers. Alfio and Alannah Marino are selling their home at 24 Cayman Cres, Raby Bay.Owners Alfio and Alannah Marino told The Courier-Mail they had embarked on a renewed push to sell their home of 15 years when market confidence started to pick up.“I feel it’s probably one of the best times for a long time (to be selling),” Mr Marino said in June. “We’re hearing from all different sources that people are coming back out again – buying with more confidence – and the upper end of the market is moving again, and the banks are more confident in starting to lend again.” The entrance to the home at 24 Cayman Cres, Raby Bay.6. 57 Stella Street, Holland Park This home at 57 Stella St, Holland Park, was one of the most popular listings in 2019.The Hamptons-style home continued to be a big trend in 2019, as proven by this five-bedroom house in Holland Park.Along with being one of the most popular listings of the year, it is also one of the few that have actually sold.Records show the property at 57 Stella Street sold for $1.645 million in June.The brand new, hi-tech home was built by Herringbone Investments, who spent $80,000 on cabinetry alone.Selling agent Ali Mohamed, of Priority Residential, said the property was developed with an emphasis on home automation and technology, with every light in the house controlled via a phone or tablet. The indoor/outdoor area of the home at 57 Stella St, Holland Park.7. 89 Longman Terrace, Chelmer This incredible home at 89 Longman Tce, Chelmer, was one of the most popular listings of 2019.More from newsParks and wildlife the new lust-haves post coronavirus10 hours agoNoosa’s best beachfront penthouse is about to hit the market10 hours agoThis award-winning riverfront estate is owned by the heir to one of Australia’s biggest fortunes.Failed restaurateur TJ Peabody created a stir when he put his lavish Chelmer on the market in August to pay back his father who bailed him out when his Brisbane restaurant empire suddenly fell over two years ago. Terrance “TJ” Peabody, son of millionaire Terry Peabody, is selling his riverside mansion at Chelmer. Photo: Lyndon Mechielsen.The property at 89 Longman Tce is one of the city’s most enviable trophy homes, boasting seven bedrooms and seven bathrooms.The classic, American-style house sits on a huge, 2400sq m parcel of riverfront land and is for sale by negotiation. Part of the sale will help the 59-year-old repay his father, rich-lister Terry Peabody, 79, believed to be worth upwards of $500 million. Inside the house at 89 Longman Tce, Chelmer.8. 121 King Arthur Terrace, Tennyson This house at 121 King Arthur Tce, Tennyson, was one of the most viewed listings of 2019.This decadent, riverfront mansion belongs to the former owner of Queensland takeaway-chicken chain, Brodie’s.Mark Brodie, who was chosen to run the state-owned Gladstone Ports Corporation after the Liberal National Party government won office in 2012, was also a political confidant of former premier Campbell Newman.The lavish estate in King Arthur Terrace, Tennyson, is like something out of the pages of F. Scott Fitzgerald’s The Great Gatsby.The property encompasses more than 3500 sqm of riverfront land, with a five-bedroom main residence, a three-bedroom guesthouse and a third building that could be used as a gym or office — all spread across three titles.Features include an eight-person spa with sweeping views, internal lift, a wine cellar, 12-seat cinema, riverside pavilion with its own kitchen and bathroom, private jetty and pontoon, in-ground pool and tennis court.It’s for sale with Glenn Gracie of Queensland Sotheby’s International Realty. This home at 121 King Arthur Terrace, Tennyson, is for sale.9. 94 Minimine Street, Stafford The house at 94 Minimine St, Stafford, has a bowling alley.Few houses in Brisbane come with their own built-in bowling alleys, let alone one in the humble northside suburb of Stafford.But this Brady-Bunch inspired home on one of the largest residential blocks in the suburb at 94 Minimine Street is an exception.The house was built into a sloping block 14 years ago. with a 23m above ground pool wrapping around two sides of the upper level where all the bedrooms and living areas are located.Following an internal water feature through the house to the back patio, the roof peels off to expose the pool and an artificial turfed backyard with golf putting green that extends almost to the rear of the property.The impression is of a single level home with only the ground level garage visible from street level.The idea that this property also houses a two-lane bowling alley, Gold Class-style cinema, games hall, wet bar and wine cellar, along with a garage for 10 cars, seems fanciful until you find an inconspicuous hallway door that leads down to the ground level.The property was snapped up for $3 million in June. This house at 94 Minimine St, Stafford, sold earlier this year.10. 558 London Road, Chandler This house at 558 London Rd, Chandler, was one of the most viewed property listings of 2019 in Queensland.Dubbed the ‘James Bond House’, this property attracted plenty of attentino when it was put up for sale in October.A modern masterpiece in a semi-rural sanctuary aptly describes the home at 558 London Rd, Chandler, which features two secret staircases and an underground garage for up to 22 cars.The six-bedroom, seven-bathroom home hit the market with $6 million hopes, but is still for sale without a price guide. In addition to the main house, there is another separate fully self-contained two-bedroom home on the 1.01ha block.Features include a 45sq m wine cellar with its own kitchenette and tasting facilities, a state-of-the-art home theatre as well as an outdoor cinema, a kitchen with butler’s pantry, an 11m x 7m pool, outdoor kitchen, pizza oven, executive office, home automation system and a gym.Marketing agent Tyson Clarke, of Queensland Sotheby’s International Realty – Brisbane, said the home had Brisbane’s biggest residential garage.“I sold the famous Batman tunnel house in Ascot for $8.8 million, which had a secret tunnel to a 10-car underground garage,” Mr Clarke told The Courier-Mail.“This has a similar feel, but this garage is double that.” A James Bond-inspired home at 558 London Road, Chandler, is for sale. Photo: Supplied.
“Whether I can play depends on my continued progress and recovery.”Woods, now ranked 711 in the world, suggested he will compete in the Turkish Airlines Open in November and the Hero World Challenge in the Bahamas in December.He also plans to take part in the Tiger Woods Invitational on 10 and 11 October.“It could be a fun fall,” said Woods. “It was difficult missing tournaments that are important to me, but this time I was smart about my recovery and didn’t rush it. But I missed competing.”Woods had a back operation in March 2014, another in September 2015 and a follow-up procedure to relieve discomfort.He missed the Masters in April 2016 for only the second time since his debut in 1995.Although he registered for the US Open in June, he pulled out a week before the tournament because he was not “physically ready”.Share this:FacebookRedditTwitterPrintPinterestEmailWhatsAppSkypeLinkedInTumblrPocketTelegram Fourteen-time major winner Tiger Woods hopes to return to action in October after more than a year out with injury.The 40-year-old American has twice had back surgery since his last appearance, at the Wyndham Championship in August 2015.He is aiming to play in the Safeway Open in California starting on 13 October.“My hope is to have my game ready to go,” said former world number one Woods.“My rehabilitation is to the point where I’m comfortable making plans, but I still have work to do.